Assistant Professor EBRU BİLGET GÜVEN
Education
Doctorate
İHSAN DOĞRAMACI BİLKENT ÜNİVERSİTESİ
Moleküler Biyoloji ve Genetik
Master's Degree
ÇUKUROVA ÜNİVERSİTESİ
Biyokimya
Bachelor's Degree
BOĞAZİÇİ ÜNİVERSİTESİ
Kimya
Research Areas
- Anti-kanser ajanların aksiyon mekanizmalarının incelenmesi
- Protein kinazlar ve inhibisyonları
- Kanser araştırmaları ve ilaç keşfi için sinyal yolağı analizi
Work Experience
2016 /
Continuing
Dr. Öğretim Üyesi
Kadir Has Üniversitesi
Administrative Duties
| Görev Adı | Görev Yeri | Başlangıç tarihi | Bitiş Tarihi |
|---|---|---|---|
| Erasmus ve Değişim Programı Komisyonu - Komisyon Üyesi(Moleküler Biyoloji ve Genetik Bölümü Temsilcisi) | Moleküler Biyoloji ve Genetik Bölümü | 01.01.2019 |
Publications
- Bilget Guven, Ebru; Durmaz Sahin, Irem; Altiparmak, Duygu; Servili, Burak; Essiz, Sebnem; Cetin-Atalay, Rengul; Tuncbilek, Meral (2023), "Newly synthesized 6-substituted piperazine/phenyl-9-cyclopentyl containing purine nucleobase analogs act as potent anticancer agents and induce apoptosis via inhibiting Src in hepatocellular carcinoma cells", RSC Medicinal Chemistry, DOI: 10.1039/d3md00440f
- Bilget Güven, Ebru; Polat, Emre Ozan; Cetin, M. Mustafa; Tabak, Ahmet Fatih; Özuğur Uysal, Bengü ; Arsan, Taner ; Kabbani, Anas; Sümeyye Berfin Gül, Houmeme Hamed (2022), "Transducer Technologies for Biosensors and Their Wearable Applications", Biosensors, Vol.12, No.6, DOI: 10.3390/bios12060385
- Bilget Güven, Ebru; Kahraman, Deniz Cansen; Aytac, Peri S.; Aykut, Gamze; Tozkoparan, Birsen; Cetin Atalay, Rengul (2022), "A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation ", Scientific Reports, Vol.12, No.1, DOI: 10.1038/s41598-022-17444-0
- Polat, Emre Ozan; Cetin, M. Mustafa; Tabak, Ahmet Fatih; Güven, Ebru Bilget; Uysal, Bengü Özuğur; Arsan, Taner; Kabbani, Anas; Hamed, Houmeme; Gül, Sümeyye Berfin (2022), "Transducer Technologies for Biosensors and Their Wearable Applications", Biosensors, Vol.12, No.6, DOI: 10.3390/bios12060385
- Kucukdumlu, Asligul; Tuncbilek, Meral; Guven, Ebru Bilget; Atalay, Rengul Cetin (2020), "Design, synthesis and in vitro cytotoxic activity of new 6,9-disubstituted purine analogues", Acta Chimica Slovenica, Vol.67, No.1, 70-82 DOI: 10.17344/acsi.2019.5196
- Tuncbilek, Meral; Kucukdumlu, Aslıgul; Guven, Ebru Bilget; Altiparmak, Duygu; Cetin-Atalay, Rengul (2018), "Synthesis of novel 6-substituted amino-9-(β-D-ribofuranosyl)purine analogs and their bioactivities on human epithelial cancer cells", Bioorganic and Medicinal Chemistry Letters, Vol.28, No.3, 235-239 DOI: 10.1016/j.bmcl.2017.12.070
- Kucukdumlu, Asligul; Tuncbilek, Meral; Guven, Ebru Bilget; Atalay, Rengul Cetin (2017), "Synthesis of some substituted 6-phenyl purine analogues and their biological evaluation as cytotoxic agents", Acta Chimica Slovenica, Vol.64, No.3, 621-632 DOI: 10.17344/acsi.2017.3419
- Durmaz, Irem; Guven, Ebru Bilget; Ersahin, Tulin; Ozturk, Mehmet; Calis, Ihsan; Cetin-Atalay, Rengul (2016), "Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status", Phytomedicine, Vol.23, No.1, 42-51 DOI: 10.1016/j.phymed.2015.11.012
- Demir, Zeynep; Guven, Ebru Bilget; Ozbey, Suheyla; Kazak, Canan; Atalay, Rengul Cetin; Tuncbilek, Meral (2015), "Synthesis of novel substituted purine derivatives and identification of the cell death mechanism", European Journal of Medicinal Chemistry, Vol.89, 701-720 DOI: 10.1016/j.ejmech.2014.10.080
Courses Offered
| Course Name | Course Code | Period |
|---|---|---|
| Biochemistry II | MBG306 | 2023/24 Spring |
| Chemistry On A Plate | KHAS1004 | 2023/24 Spring |
| Virtual Basic Lab | MBG208*1 | 2023/24 Spring |
| Biochemistry I | MBG305*1 | 2023/24 Fall |
| Biochemistry I | MBG305*1 | 2024/25 Fall |
| Cancer Biology | MBG433 | 2024/25 Fall |