Prof. Dr. Kemal YELEKÇİ

Titles

Start End Title Place
01 July 2001 01 September 2007 Dean, Faculty of Science and Arts Kadir Has University
01 January 2001 31 December 2003 Vice rector Kadir Has University
01 September 1998 01 July 2001 Dean, Faculty of Science and Arts Marmara University

Career

Start End Work Position
01 January 1987 01 January 1988 Northwestern University – Department of Medicinal Chemistry Post-doc reseracher
01 January 1988 31 December 1989 Ege University, Department of Chemistry Asst. Prof.
01 January 1990 01 January 2001 Marmara University, Department of Chemistry Assoc. Prof.
01 January 2001 - Kadir Has University, Department of Bioinformatics and Genetics Prof. Dr.

Education

Education University Department Date
Ph. D. University of Ohio Department of Organic Chemistry 1987
Master's Çukurova University Department of Organic Chemistry 1981
B.Sc. METU Department of Chemistry 1979

Interests

Computer-aided drug design Molecular Dynamics and quantum mechanic methods
Computational chemistry

Courses

Code Course Name Course Location Semester
CH-500 Nuclear Magnetic Spectroscopy & Applications Marmara University Spring 1990-91 - Spring 1995-96 - Spring 1999-2000
CH-450 Spectroscopic Identification of Organic Compounds Marmara University Spring 2000-01 - Spring 1999-2000
PC-157 History of Science I Kadir Has University Fall 2013-14
BIO-531 Essential Cell Biology Kadir Has University Fall 2012-13
CH-101 General Chemistry Kadir Has University Fall 2013-14, Fall 2012-13
BIO-206 Organic Chemistry II Kadir Has University Spring 2014-15
BIO-201 Organic Chemistry I Kadir Has University Fall 2014-15
BIO-622 Special Topics in Medicinal Chemistry Kadir Has University Spring 2014-15
BIO-520 Organic Chemistry of Drug Design and Drug Action Kadir Has University Spring 2014-15
BIO-511 Introduction to Bioinformatics Kadir Has University Fall 2014-15

Projeler

Start Start Project Name Project Type Word Fund Committee
27.4.2020 27.4.2022 Kanser tedavisinde kullanılmak üzere histon deasetlaz HDAC6 ve HDAC10 enzimlerine karşı in siliko tarama ve medisinal kimya yaklaşımlarını kullanılarak etkili ve seçimli yeni inhibitörler geliştirmek Araştırma Projesi Yürütücü TÜSEB (Türkiye Sağlık Enstitüleri Başkanlığı)
Mart 2020 Mart 2022 Molecular modeling, synthesis, and potential anticancer activity of heteroaryl sulfanyl acetamide derivatives through apoptosis, angiogenesis and mPGES-1enzyme (Microsomal prostaglandin E2 synthase1) inhibiton Araştırma Projesi Araştırmacı TÜBİTAK 1001. SBAG 218S549
Mart 2016 Mart 2016- Mart 2020 Development of Novel Synthetic Agents for Prostate Cancer Treatment Araştırma Projesi Araştırmacı TÜBİTAK-1003. 2015S009
Mart 2015 Mart 2019 Epigenetic Chemical Biology (EPICHEM) Araştırma Projesi Yürütücü COST Action. (CM1406)
Kasım 2013 Kasım 2017 Training in Neurodegeneration, Therapeutics Intervention & Neurorepair – TINTIN Araştırma Projesi Yürütücü FP7. Marie Curie Initial Training Networks (ITN). Call: FP7-PEOPLE-2013-ITN. Project ID: 608381

Yayınlar

Title Type Publishing House Year Released Month City Journal Type
Synthesis, Anticancer Agents and Molecular Docking of (S)- Naproxen-1, 2, 4-Triazole Derivatives Araştırma Makalesi EMB 2020 01 Europe European Journal of Medicinal Chemistry, 208.112841
Drug repurposing for coronavirus (COVID-19): In silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes Araştırma Makalesi Taylor and Francis 2020 01 ABD Journal of Biomolecular Structure and Dynamics, 1-13. doi:10.1080/07391102.2020.1758791
New 2‐Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors Araştırma Makalesi ACS 2021 01 ABD Journal of Medicinal Chemistry
Synthesis, Anticancer Activity on Prostate Cancer Cell Lines and Molecular Modeling Studies of Flurbiprofen-Thioether Derivatives as Potential Target of MetAP (type II). Medicinal Chemistry Araştırma Makalesi Bentham 2020 01 UK Medicinal Chemistry, 16(6), 735-749, 2020. doi:10.2174/1573406415666190613162322
Identification of potential inhibitors of human methionine aminopeptidase (type II) for cancer therapy: Structure-based virtual screening, ADMET prediction and molecular dynamics studies. Araştırma Makalesi Elsevir 2020 01 ABD Computational Biology and Chemistry, 86 doi:10.1016/j.compbiolchem. 2020.107244, (IF: 3.107).